Do you have cardiovascular disease and elevated cholesterol levels?
See if you qualify to participate in the PREVAIL study
PREVAIL is clinical research study evaluating the safety and effectiveness of an investigational drug in people who have cardiovascular disease. The study drug is designed to lower cholestrol specifically low-density lipo-protien cholestrol(LDL-C), known as the harmful or "bad" form of cholestrol.
Study Overview
Have study clinic and telephone visits for about 3 to 4 years.
Take one tablet of either the study drug or a placebo(no active ingredients) by mouth once daily.
Continue taking your medication to lower cholestrol that was prescribed by your general practitioner(if applicable).
Follow a cholestrol-lowering diet and make lifestyle changes as instructed you general practitioner
Have 1 follow-up visit after your last dose of the assigned study drug or placebo(via telephone).
Key study requirements
You have a history of cardiovascular disease.
You are 18 years of age or older and have elevated bad "cholestrol" levels:
Fasting LDL-C of 100 mg/dL (2.6 mmol/L) OR greater.
OR
Fasting LDL-C of 55 mg/dL (1.4 mmol/L) to 100 mg/dL (2.6 mmol/L) with at least 1 of the following risk factors:
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Recent heart attack (about 3 months ago to less than 1 year).
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Type 2 diabetes;
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Other blood test results such as fasting triglycerides greater than 150 mg/dL(1.7 mmol/L), or fasting HDL-C less than 40 mg/dL(1.0 mmol/L)(the "good" form of cholesterol).
You are taking medication(s) to lower cholesterol(if applicable) such as statin(s).
You may be eligible if you are taking a low dose of statin medication or a combination of cholesterol-lowering medications